Mortality selection in a genetic sample and implications for association studies

Author/s: 
Ben Domingue, Daniel Belsky, Amal Harrati, Dalton Conley, David Weir, Jason Boardman
Year of Publication: 
2017

Mortality selection occurs when a non-random subset of a population of interest has died before data collection and is unobserved in the data. Mortality selection is of general concern in the social and health sciences, but has received little attention in genetic epidemiology. We tested the hypothesis that mortality selection may bias genetic association estimates, using data from the US-based Health and Retirement Study (HRS).

Primary Research Area:

Topic Areas:

APA Citation

Domingue, B., Belsky, D., Harrati, A., Conley, D., Weir, D., & Boardman, J. (2017). Mortality selection in a genetic sample and implications for association studies.